LATER.--In another part of this issue is reproduced the Governor's message vetoing this bill. It is excellent reading. SANITARY MILK SUPPLY FOR LOUISVILLE. With the purpose in view of getting a more sanitary milk supply in Louisville, a conference of dairymen, wholesale and retail milk dealers, railroad officials, city and State health officials was held in the Council Chamber of the City Hall on March 22. The discussion was opened by Mr. R. M. Allen, head of the Pure Food Department of the State Experiment Station, at whose instance the meeting was held and before the conference was adjourned it was agreed that a concerted effort would be made to raise the standard of the milk supply of the city. It may be that as a result of the conference refrigerator cars may be used for bringing milk from the various supply points into Louisville. In order that all dairymen supplying milk to Louisville may attend one or more of these milk conferences it was decided to hold them first at one supply point, then another, until all the territory has been covered. Notes Dr. Theodore Frantz, aged forty-eight, died at his residence March 13. Dr. Frantz was born in Alsace and came to Louisville thirty years ago. He was graduated from the University of Louisville, practiced medicine a few years and then conducted a drug store until a few years ago when he resumed the practice. of medicine. The provost and trustees of the Uni versity of Pennsylvania gave a reception in the hall of the Medical Laboratory Building, 37th and Hamilton Walk, at 2 p. m., Saturday, March 30, 1912, on the occasion of the unveiling of a bronze medallion in honor of Dr. Crawford Williamson Long (1839, Med. U. of P.), who first made use of ether as an anesthetic for surgical purposes on March 30, 1842. Addresses were made by Dr. J. William White and Dr. J. Chalmers Da Costa, and music rendered by the University Glee Club. Dr. Thomas Stone Lewis, of Lexington, Ky., died on March 24th, after an illness of several weeks. He was born August 21, 1873, at Bloomfield, and was the son of Dr. S. M. Lewis. He was a graduate of the Kentucky State University in 1895, and from the University of Louisville Medical Department in 1898. He was the first interne of the Good Samaritan Hospital in Lexington and wa sfor a long time associated with Dr. B. L. Coleman, of Lexington. In 1905 and 1908 he was bacteriologist at the Eastern State Hospital. Book Reviews The Surgery of Oral Diseases and Malformations. Their Diagnosis and Treatment. By George V. I. Brown D. D. S., M. D., Oral Surgeon to St. Mary's Hospital and to the Children's Free Hospital, Milwaukee; Professor of Oral Surgery, Southern Dental College, Atlanta, Ga. Octavo, 740 pages, with 359 engravings and 21 plates. Philadelphia and New York: Lea & Febiger, publishers, 1912. Cloth, $6.00 net. During the last ten years of the thirty which have been devoted to surgery, the author has limited his practice to the treatment of oral diseases and malformations. He has successfully presented a book which can be used as a text book in college work and as a reference work by the graduate. It is, of course, to the chapters on hare lip and cleft palate that we naturally turn, knowing how much work the author has done upon these deformities and because of its great importance. In the text, which has been most carefully prepared, many original drawings have been inserted to show each operative step in their correction, and many original pictures of the author's cases showing the results of corrections. One phase of the work of the oral surgeon, which is described, is the separation of the maxillæ for the correction of nasal defects and the control of pathological influences that may affect the nose and associated parts. The operative treatment of diseases of the nose and throat has been omitted, as it lies outside of the province of the oral surgeon. Dr. Brown gives prominence to the formula for injection in the treatment of trigeminal neuralgia as suggested by Dr. Hugh T. Patrick, of Chicago-cocaine, chloroform, alcohol and water. The chapter upon carcinoma is quite complete, being well illustrated-some of them in colors. He advocates the use of the X-rays upon the open wound after. operation for cancer of the lip. Health and Medical Inspection of School Children. By Walter T. Cornell, M. D., Director of Medical Inspection of Public Schools, Philadelphia; Lecturer on Child Hygiene, University of Pennsylvania, etc., etc. Illustrated with 200 half-tone and line engravings, many of them original. Philadelphia: F. A. Davis Co., publishers, 1912. No more important subject is before. the community than the subject of this book. Child welfare work is causing intelligent comment and interest everywhere, and this phase of the work, Medical Inspection of Schools, is one of the most important. The author has an experience of examination of 35,000 school children, and it is from this standpoint that the facts have been presented. In the first part has been discussed the administrative parts of the work, appointment of inspectors, their efficiency, number, compensation, facilities for inspection, etc.; the inspection of children, correction of defects, results of medical inspection and present status of medical inspection in the United States. The all-important subject, school sanitation, under the chapter head of Hygiene is then discussed, and in Chapter III, Defects and Diseases are carefully and thoroughly discussed in detail-The Eye, Nose and Throat, Ear, Teeth, Nervous System, Mental Deficiency, The Skeleton, Nutrition, The Skin, Speech, Infectious Diseases, Prevalence of Defects and Dis eases. The book is written in a very forceful and fascinating manner. Nothing seems to have been forgotten or overlooked, and we trust a very wide sale and distribution may be had of the book. Pellagra. By George M. Niles, M. D., Professor of Gastroenterology and Therapeutics in the Atlanta School of Medicine, Atlanta, Georgia. Octavo of 253 pages, illustrated. Philadelphia and London: W. B. Saunders Company, 1912. Cloth, $3.00 net. The author has presented this book, recording his own views and convictions, ready to make the necessary amends should subsequent experience convince him that he has fostered an error. Chapter I is devoted to general considerations, historic and otherwise, in which is traced the history of the disease in many countries. The history of pellagra in the United States is discussed in Chapter II, which is an interesting account of apathy on the part of the general profession in regard to this important condition. The Etiology of Pellagra is discussed in Chapter III. The following causes are given: Maize, Sporisorium Maidis, the best-known parasite of spoiled corn, penicillium glaucum; the toxicochemical idea. This chapter is closed with Lombroso's theory: "In pellagra, then, we are dealing with an intoxication produced by poisons developed in spoiled corn through the action of certain micro-organisms, in themselves harmless to man.” Then follow chapters on Symptomatology and Course of Pellagra; Clinical Reports of Cases from Different Sources; Pathology and Morbid Anatomy; Diagnosis, Course and Progress; The Treatment, a Discussion of Different Methods; Prophylaxis, and Description of Some Recent Experiments on Animals and Deductions therefrom. The author states pellagra is a serious disease; but gives a favorable prognosis in those early cases, recognized before cachexia has set in, cases in the intermittent stage; where little involvement of the nerve centers is apparent, cases which possess enough intelligence and perseverance to continue treatment for a long time, and cases with strong ancestry, without syphilitic and other hereditary taint. A steady drinker has but little chance to recover. The book is of great interest, and cannot help but be an aid to clinicians who may see these cases. Recent Methods in the Diagnosis and Treatment of Syphilis (The Wassermann Serum Reaction and Ehrlich's Salvarsan). By Carl H. Browning, M. D., Lecturer in Clinical Pathology, University of Glasgow, etc., and Ivy McKenzie, M. A., B. Sc., M. B., Ch. B., Director Western Asylum Research Institute, Glasgow, etc. In collaboration with John Cruikshank, M. B., Ch. B.; Charles G. A. Chislett, M. B., Ch. B.; Walter Gilmour, M. B., Ch. B.; Hugh Morton, M. B., Ch. B., with an Introduction by Robert Muir, M. A., M. D., F. R. S., Professor Pathology in University of Glasgow. Philadel phia and New York: Lea & Febiger, 1912. With such an array of talent contributing to this book, one would have great hopes of it. The research work which it represents was made possible largely through the Carnegie Trust. The book deals with the nature of the Wassermann reaction and the results ob tained by its application, and the therapeutic effects of salvarsan. An understanding of the principles of the Wassermann reaction is a requisite to its application and the authors have expounded it thoroughly. Reference is made in the introductory chapter to the birth of a syphilitic child of a mother, apparently healthy, and the evidence at hand to prove she has reacted to the virus already. It is stated that a cure has been effected by salvarsan in a large proportion of cases. The authors dwell upon the effect of salvarsan upon the tissues when given hypodermically. The gathering together of all the information regarding salvarsan, when its general use has become so much restricted owing to a reaction against it, and a dispassionate description of its use, near and remote effects, is very welcome. Progressive Medicine. A Quarterly Digest of Advances, Discoveries and Improvements in the Medical aud Surgical Science. Edited by Hobart Amory Hare, M. D., Professor of Therapeutics and Materia Medica in the Jefferson Medical College, Philadelphia, Assisted by Leighton F. Appleman, M. D., Instructor in Therapeutics, Jefferson Medical College, Philadelphia. Philadelphia and New York: Lea & Febiger, December, 1, 1911. The following contributors have prepared this volume: Dr. R. S. Levenson, Diseases of the Digestive Tract and Allied Organs-the Liver, Pancreas and Peritoneum; Dr. John Rose Bradford, Diseases of the Kidneys; Dr. Charles W. Bonney, Genito-urinary Diseases; Dr. Joseph C. Bloodgood, Surgery of the Extremities, Shock, Anesthesia, Infections, Fractures, and Dislocations and Tumors; Dr. H. R. M. Landis, Practical and Therapeutic Referendum. These digests are most thorough in every detail, considering as they do the latest in every branch of medicine, surgery and therapeutics. Minor and Emergency Surgery. By Walter T. Dannreuther, M. D., Surgeon to St. Elizabeth's Hospital and to St. Bartholomew's Clinic, New York City. 12mo volume of 226 pages, illustrated. Philadelphia and London: W. B. Saunders Company, 1911. Cloth, $1.25 net. This book has been written with a view to the needs of the hospital interne, the author state "exclusively," but the many good points so succinctly put will be found of service to practitioner as well. Hospital internes will benefit by the book as well as the ambulance in surgeon emergencies. In a book of this kind ample opportunity was afforded for stress to have been laid on the result too often obtained by an interne in a hospital, that he alone knows. The term "big head" can be applied far too frequently to the interne recently graduated or about to leave the hospital. This is touched upon in the introductory chapter, but not emphasized sufficiently Much of value can be found in the 200 pages of this book. A Handbook of Practical Treatment. In Three Volumes. By 82 Eminent Specialists. Edited by John H. Musser, M. D., Professor of Clinical Medicine, University of Pennsylvania; and A. O. J. Kelly, M. D., Late Assistant Prefessor of Medicine, University of Pennsylvania. Volume III. Octavo of 1,095 pages, illustrated. Philadelphia and London: W. B. Saunders Company, 1912. Per volume: Cloth, $6.00 net; Half morocco, $7.50 net. Thirty-eight contributors have furnished the matter for this, the last of the series of this excellent handbook. In this volume are considered Constitutional Diseases; Diseases of the Respiratory System; Digestive and Urinary Systems; Nervous System, and Diseases of the Mind. It is manifestly impossible to consider in detail all of the contents of this excellent volume. The contributors are all eminent in their special field of observation and practice; they have given much thought and attention to the chapters contributed by them, and the results are such that both the distinguished editor and publishers should be proud. These three volumes are essential to every well-balanced library. Blair's Pocket Therapeutics: A Practitioner's handbook of Medical Treatment. By Thomas S. Blair, M. D., Neurologist to Harrisburg, Pa., Hospital; Author of "A System of Public Hygiene," "Blair's Practitioner's Handbook of Materia Medica," Member of the Harrisburg Academy of Medicine, American Medical Association, etc. 373 pages, special Bible paper; bound in limp leather; price, $2.00. Published by The Medical Council Co., Forty-second and Chestnut streets, Philadelphia, Pa. This little pocket-size book contains an intelligent discussion of the best methods of treatment based on scientific principles, with a well-tried, reliable formula occasionally to illustrate the application of the principles. The book contains a Table of Large, Medium and Small Doses. The diseases described are divided into related groups, each group occupying a chapter, with an alphabetical index for instant reference to any particular disease. Funk & Wagnalls Company have secured the American rights to "A System of Surgery," edited by C. C. Choyce, Dean of, and Teacher of Operative Surgery in the London School of Clinical Medicine, (Post-Graduate,) etc. J. Martin Beattie, Professor of Pathology and Bacteriology and Dean of the Faculty of Medicine in the University of Sheffield, is the Pathological Editor of this important new work. It will be published in three octavo volumes and profusely illustrated with colored, black-and-white, and text illustrations. Each branch of surgery is treated by the foremost specialists in that particular branch in Great Britain so that the work will really comprise the whole field of surgery from the viewpoint of the foremost British practitioners. Volume I will be ready about the middle of April and the remaining two volumes will be published about Autumn, 1912. The price of the work will be $21.00 per set. Original Contributions THE HYPOPHYSIS CEREBRI - ITS LOUISVILLE, KY. There are but few chapters in the history of medicine which reflect more credit upon experimental medicine and physiological research than those which tell of the work done on the ductless glandsfew subjects which are of more importance to the practitioner than the understanding of the functions of these bodies --the states of health which follow either over or under activity of these organs at various periods of life. Were it possible to separate clearly the activities of these bodies from one another it would soon develop that in general influence upon metabolism the pituitary is an organ of the highest importance, standing in this respect in close relation to the thyroid, and when some unknown factors are cleared up, may appear even more closely bound up with the essential processes of life, for it is a known fact that animals survive complete thyroidectomies longer than they do the total loss of the hypophysis. The pituitary is, as is well known, a gland whose anterior portion is of one origin-its posterior of another. Their structure and functions differ widely and *Read before the Louisville Clinical Society. NUMBER 12 the anterior portion of the gland is, strictly speaking, the ductless part, the colloid secretion of the posterior lobe having been seen escaping through the infundibular part by Herring and Schafer and Cushing and Goetch into the third ventricle and Cushing has demonstrated the presence of the pressor principle of this portion of the gland in the cerebrospinal fluid. The larger, or anterior portion of the pituitary body, has a much more abundant blood supply than the posterior part, its vessels are of the sinus-oidal type and its secretion doubtless escapes into these channels, and so reaches the general circulation. With reference to the functional disturbances of any of the glands influencing metabolic processes, it may be stated! that the results vary as to the character of the disease process whether a state of hyper- or hypo-activity is present and whether the malign influence is exerted during the growing years or after the stage of adolescence is reached. In the case of the pituitary the matter is further complicated by the part of the gland involved, the anterior presenting one train. of symptoms, the posterior another and finally whether the entire body is concerned in the pathological process. Pierre Marie was the first, in 1885. to connect akromegalie with tumors of the pituitary. Since then many observers have proved this observation to be correct |