Cutaneous BiometricsDoris Schwindt, Howard I. Maibach Springer Science & Business Media, 2001 M01 31 - 358 pages Biometrics in dermatology is an essential tool where data evaluation results in valid interpretations. This book will be the first in this area. One part of the book will describe principal aspects of dermatological research focussing on practical advice. A special part will cover applied biometrics to provide the clinician and researcher with state-of-the-art guidelines to assess the severity of common skin diseases. An additional aspect that will be of interest to pharmacologists addresses pharmacologic assays. |
Contents
Statistics in Clinical Research | 3 |
The CaseControl Study | 23 |
Principles for the Conduct of Nondrug Clinical Studies | 37 |
Questionnaire Design in Skin Disease Epidemiology | 43 |
Noninvasive Evaluation of Skin Properties | 55 |
Scale Development for Clinical Assessment | 57 |
Evaluation of Cosmetics by Sensory Assessment | 65 |
Cutaneous Bioengineering | 81 |
Measurement in Scleroderma Clinical Trials | 183 |
Quantification of Wound Healing | 205 |
Design of Clinical Trials to Evaluate Antimycotic Agents in the Treatment of Dermatophyte Infections | 221 |
Sites of Contact Dermatitis in Relationship to Particular Allergens A FollowUp Study | 233 |
Evaluating Surveillance Systems in Contact Dermatitis | 243 |
Sodium Lauryl Sulfate Water Soluble Irritant Dermatitis Model | 257 |
Quaternium18 Bentonite in the Prevention of Allergic Contact Dermatitis | 269 |
Personal Cleansers Irritation and Moisturization | 273 |
Skin Diseases and Therapy | 91 |
Atopic Dermatitis Severity Scoring | 93 |
A Review of the Use of Essential Fatty Acid Supplementation in Atopic Dermatitis with Emphasis on the Methodology of Trial Design | 109 |
Severity Scoring of Atopic Dermatitis | 119 |
A Metric for Acneiform Eruptions of the Face | 129 |
Toward a New Psoriasis Severity Scoring Using Bioengineering Techniques | 149 |
Epidemic of Melanoma How Real Is It? | 159 |
Prognostic Models in Melanoma | 167 |
Photoaging | 173 |
Pharmacologic Assays | 287 |
Small Plaque Assay | 289 |
Application of the Minolta Chromameter to the Assessment of CorticosteroidInduced Skin Blanching | 295 |
Assaying for Bioavailability in Acne | 307 |
In VitroIn Vivo Correlations | 315 |
Pharmacoeconomics | 331 |
Pharmacoeconomics and Outcomes Research | 333 |
The Cost of Atopic Eczema to the Society An International Perspective | 343 |
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Common terms and phrases
acid acneiform Acta Derm Agner allergen allergy analysis application assay assessment atopic dermatitis atopic eczema baseline Berardesca bioengineering blanching chromameter cleansing products Clin clinical trials Contact Dermatitis controls correlation corticosteroid cosmetics criteria Cutaneous Biometrics Cyclofenil Dermatol Dermatology dermatophytes detect diagnostic drug effect Elsner epidemiological erythema evaluation exposure factors grading guidelines healing Hour DD incidence investigator involvement irritant lesion number lesions Maibach melanoma method moisturizing observed outcome measures P-value parameters patch test patients personal cleansers placebo population psoriasis quantify questionnaire Rajka Raynaud's phenomenon relevant reported response salicylic acid sample scale Schwindt and Howard scleroderma SCORAD scoring system sensitivity Serup Severity Scoring significant skin condition skin disease skin score soap sodium lauryl standard statistical Stockh stratum corneum subjects surface surfactants symptoms systemic sclerosis technique TEWL therapy tinea topical transepidermal water loss treatment tretinoin valid values variability Venereol visual vitro vivo wound