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MATERIA MEDICA AND THERAPEUTICS.

Dose, into Relation

Especially with Reference to Repeated Administration of Indaconitine, J. T. Cash-29, May 23, p. 1213.

Adrenalin and Osteomalocia (Adrénaline et astéomalacie), de Bovis-184a, May 20, p. 241.

Alkaloidal Medication, Principles of, W. C. Abbott-4, June, p. 765.

Alkaloids, Proteid Digestion and, J. Burke101, June, p. 22.

Alkaloids in the Guatemala Highlands, C. F.
Secord-4, June, p. 769.

Alkaloids, The Principal, A Study of, J. M.
French-4, June, p. 777.
Alkaloids, Therapeutic Nihilism and the, M.
Shadid-4, June, p. 779.
Alphamonobrom -isolvalerylurea,

A New

Nerve Sedative and Somnifacient, W. H.
Porter-28, June 25, p. 971.

Alypin, A New Local Anaesthetic (L'alypine, nouvel anesthésique local), Sorlat—64g, May 2, p. 351.

Antipyretics, Mode of Action of a Few (Ueber die Wirkungsweise einiger Antipyretica), Cloëtta-56a, May 15, p. 314. Antipyresis, The Question of (Zur Frage der Antipyrese), Staehelin-196b, May, p. 219. Antirabic Serum, Preparation and Use of, and on Rabicidal Properties of Serum of Patients Undergoing Antirabic Treatment; Note on Blood of a Hydrophobia Patient, D. Sample-95, June 6, p. 1611. Antistreptococcus Serum, Results of, in Scarlatina, H. W. Robinson-167, June, p. 384.

Arsenic, Abuse of, in Treatment of Diseases of Skin and Deleterious Effects that May Occur, J. F. Schamberg-196, June, p. 403. Arsenic, Action of, on Human Economy from Therapeutical Standpoint, J. F. Marrs91d, June, p. 324.

Arsenic, Weak, Nervous Children and, E. F. Christin-28d, May, p. 201.

Atoxyl in Treatment of Syphilis, J. Dardel-
6, June, p. 249.
Auto-protective Resources of Body-New
Foundation for Scientific Therapeutics;
C. E. de M. Sajous-200, May, p. 201.
Bacterial Vaccines, Treatment of Infective
Diseases by, F. G. Bushnell-143, June,
p. 403.

Bath Treatment at Mt. Clemens in Reference to Nervous Patients, R. Leuschner-86b, June, p. 295.

Bier Hyperemia Method, How to Enhance Its Curative Efficiency, C. E. de M. Sajous-200, June, p. 281.

Bier's Hyperamic Treatment, with Demonstration of Technique, F. Winnett-134, June, p. 330.

Bismuth Subgallate, J. A. Burnett-131, June, p. 105.

Camphoric Acid, Action and Uses, M. V. Tyrode-28, June 11, p. 908.

Carbonic Acid Gas Baths, Natural and Ar tificial (Bains carbogazeux naturels et artificiels), Mougeot-179b, May 1, p. 289; May 15, p. 306.

Cataphoric Sterilization, Cancer and Its Treatment by, G. B. Massey-82, June, p. 317.

Creosote, Codliver Oil, Russel's Emulsion and Ichthyolated Emulsion Compound in Tuberculosis, J. R. Williams-41, June, p. 336.

Cum Grano Salis, R. L. Wood-155, June, p. 316.

Cupping, Therapeutics of, C. F. Hope-134,
June, p. 243.
Digitalis and Its Uses, St.G. T. Grinnan-41,
June, p. 326.
Digitalis, Protracted Use of, R. E. Achert-
95, June 6, p. 1619.
Digitalis Therapeutics, E. M. Howard-68,
June, p. 415.

Digitalis, Use and Abuse of, T. C. Janeway-
8, June, p. 781.
Diphtheria Antitoxin Refined and Concen-

trated by Gibson's Method, Results Obtained from Use of, R. E. Wodehouse150, June 27, p. 1242.

Diphtheria Antitoxin, Urticaria Following the Second Administration of, A. W. Blain, Jr.-123, June 6, p. 940. Drugs, Indigenous, A. K. Bose-170, June, p. 101.

Drugs, Should Druggists Manufacture and Dispense Mixtures of Their Own, and is it Advisable that Doctors Dispense Their Own? H. E. Irish-73c, June, p. 644.

Electricity, Treatment of Neurasthenia and Occupation Neuroses with, W. H. White -82, June, p. 307.

Electrotherapeutics

and Electrodiagnosis, Practical (Elektrodiagnostik und Elektrotherapie des Praktikers), Fuchs-137, May 16, p. 1121.

Formaldehyde and Malignant Tumors, Lang

held-196a, June, p. 61.

Formic Acid, Treatment of Tuberculosis with, C. F. d'A. Francis-119, June, p. 271. Gelsemine in the Morphine Habit, W. F. Waugh 177, XXX-2, p. 107.

High Frequency Currents, The Principle of (Le principe des courants de haute fréquence), Zimmern-174c, May 2, p. 283.

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Oxygen in Medicine and Surgery, W. S. Bainbridge-152, June, p. 281.

Plasma Solution in Affections of Eye, Nose
and Throat, M. McFarlane-134, June,
p. 335.
Physio-therapeutic Methods in Chronic Dis-
eases, C. Pope-45, June 6, p. 665.
Pneumatic Cabinet, What Diseases Are

Amenable to Treatment in (Welche
Krankheiten sind im pneumatischen
Kabinette zu behandeln)? Aron-196c,
May, p. 195.

Potassium Iodide, Mode of Action of (Ein Beitrag zur Kenntnis der Wirkungsweise des Jodkaliums), Zwintz-208, May 14, p. 724.

Psychotherapy, P. C. Hunt-202, June 26, p. 121.

Psychotherapy, B. Onuf-79, June 6, p. 1892. Psychotherapy, General Aspects of, J. Grinker-73c, June, p. 625.

Psychotherapy, Remarks on, C. Lull-1, June, p. 395.

Psychotherapy, Treatment by Rest, Seclusion, etc., in Relation to, S. W. Mitchell79, June 20, p. 2033.

Quinine Injections, Accidents After (Accidents consécutifs aux injections de quinine), de Gauljac-174c, May 13, p. 306.

Rachisan, A New Antirachitic (Ueber Rachisan, ein neues Antirachitikum), Weissmann-40c, May 23, p. 533.

Radiant Energy from High Power Incandescent Light, Clinical Use of, A. C. Geyser-111, June, p. 297.

Radiotherapy, Evolution of, A. Béclere-149, June, p. 975.

Remedies, 100, A Selection of, J. A. Burnett131, June, p. 114.

Rest Cure, The Essence of the, J. M. Taylor200, June, p. 275.

Rest in Bed, Therapeutic Value of, W. F. Milroy-206, June, p. 296.

Salicylate of Soda, Use of, in Accidental and Surgical Trauma, M. Monae-Lesser-126, June, p. 440.

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AN INTERNATIONAL MONTHLY REVIEW OF CURRENT MEDICAL LITERATURE

Vol. XIV

AUGUST 25, 1908.

THE PROGRESS OF MEDICAL SCIENCE.

GENERAL MEDICINE.

UNDER THE CHARGE OF

HENRY H. PELTON, M.A., M.D.,

Adjunct Assistant Attending Physician to Bellevue Hospital; Chief of Medical Clinic, Presbyterian Hospital Dispensary.

The Symptoms and Kolmer (University Treatment of Inter- of Pennsylvania mittent Lameness. Medical Bulletin, May, 1908) discusses the symptomatology and treatment of intermittent claudication thus:

No. 8

ness.

"The syndrome of intermittent lameness is more or less typical of the condition. It is always important to separate the central type from the peripheral, because this is quite essential from the standpoint of prognosis and treatment. Usually the most characteristic symptom is the intermittent or paroxysmal lameThe patient may have experienced for a long time ere the symptoms become typical vague pains in the legs, which are dismissed with a diagnosis of rheumatism, nervousness and the like. While it may be difficult to make a correct diagnosis at that time, yet it is just then that we can hope to benefit our patient most and prevent the onward progress of the disease. The paroxysms are produced by increased muscular activity. During rest the patient experiences nothing abnormal, and he can get up and walk about for a time with perfect ease. Gradually, however, after he has covered a certain distance, depending upon the severity of the

case, he experiences a feeling of numbness, weakness or pricking sensations, or simply an aching or stiffness of the calf muscles, producing the characteristic lameness. If activity is persisted in these symptoms become progressively worse, until he is forced to halt and rest. The pain is then quite severe and the muscles are cramped, stiff and rigid, and the parts may be pale or cyanotic. Gradually the pain diminishes, the muscular spasm relaxes and the former state is restored. Such is commonly the patient's description of his trouble. The results of our examination of such a case will depend upon whether it is of peripheral or central type, and if the former, whether the sclerotic or vasomotor element predominates. If of the peripheral type, palpation of the larger arterial vessels of the legs, as the posterior tibial and dorsalis pedis arteries, may reveal marked sclerosis and a weakness, or even absence, of the pulse, being usually for some unknown reason more marked on the left side. If the case is due chiefly to vasomotor spasm the parts will be found quite pale during a paroxysm, following which the pulse is about normal. Sensation is

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